In the face
of the rapid developments in sleep medicine, this book seeks to present the
current knowledge in the pathophysiology, clinical presentation, diagnosis, and
treatment of sleep apnea. New physiological approaches to modeling sleep and
recent pathophysiologic findings in upper airway mechanics as well as the
importance of inflammatory and oxidative processes and the underlying genetic
aspects are discussed to open up new avenues of investigation for better
understanding and improved therapeutic options. Besides the well-known CPAP
therapy, chapters describe novel therapeutic methods that are currently under
investigation and highlight their future prospects, limitations as well as
recommendations for practice. The influence of breathing disturbances on the
cardiovascular system during sleep is significant. Reviews of central sleep
apnea and of cardiovascular complications of sleep-disordered breathing
therefore play an important role in this edition. Some of the chapters are
dedicated to specific aspects in children, in the elderly and in pregnancy and receive
special attention as sleep apnea is relevant to all ages. The excellent
contributions to this volume will be stimulating reading to pneumologists,
sleep and ENT specialists, neurologists, dental surgeons, cardiologists,
obstetricians, general practitioners as well as public health specialists.
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