Diffuse Parenchymal Lung Disease

Diffuse parenchymal lung disease (DPLD) represents a large and heterogeneous group of disorders. Although new insights into the pathogenesis and new techniques such as high-resolution-CT have led to a better understanding of DPLD, clinical management remains a challenge. This volume is designed to become a valuable aid in the diagnosis and management of DPLD. It starts with general topics such as a new classification system for DPLD, the general diagnostic approach, and clinical evaluation of the patient by radiology, histological patterns and bronchoalveolar lavage. This is followed by consideration of some basic aspects such as the genetics of DPLD, the principles of granuloma formation, pulmonary fibrogenesis and vasculitis, as well as novel treatment approaches. A large part of the book consists of disease-specific chapters, which discuss granulomatous disorders, idiopathic pulmonary fibrosis and other entities of idiopathic interstitial pneumonia, the collagen vascular diseases, drug-induced infiltrative lung disease as well as orphan diffuse lung diseases including Langerhans' cell histiocytosis, lymphangioleiomyomatosis and pulmonary alveolar proteinosis. Special chapters on DPLD in children and lung transplantation for end-stage fibrosis complete this comprehensive publication. Written by internationally known experts, this well-organized volume is recommended to a wide audience including respiratory physicians in training, practice and research as well as radiologists and pulmonary pathologists.

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Diffuse Parenchymal Lung Disease (Progress in Respiratory Research)